The group with isolated relative memory impairments had higher proportions with в‰Ґ APOE Оµ4 allele, more extensive Alzheimer's-related neuropathology, and higher proportions with other Alzheimer's dementia genetic risk variants.ДЄ cognitive subgrouping strategy may identify biologically distinct subsets of people with Alzheimer's dementia.ДЄlzheimer's disease Cognition Endophenotypes Genetics Heterogeneity Neuropathology Subgroups.Д¬opyright В© 2017 the Alzheimer's Association. Some participants had isolated relative impairments in memory (148, 18%), visuospatial functioning (117, 14%), language (71, 9%), and executive functioning (66, 8%). There were 393 (48%) with no domain with substantial relative impairments. We compared demographic, neuropathology, and genetic findings across groups defined by relative impairments.Дuring 32,286 person-years of follow-up, 869 people developed Alzheimer's dementia. We identified domains with substantial impairments relative to that average. We determined individual averages across memory, visuospatial functioning, language, and executive functioning. We analyzed cognitive data from people with incident late-onset Alzheimer's dementia from a prospective cohort study. There may be biologically relevant heterogeneity within typical late-onset Alzheimer's dementia. 13 Department of Neurology, Boston University School of Medicine, Boston, MA, USA.12 VA Puget Sound Health Care System, Geriatric Research Education and Clinical Center, Seattle, WA, USA Department of Neurology, University of Washington, Seattle, WA, USA.11 Department of Pathology, University of Washington, Seattle, WA, USA.10 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.9 College of Arts and Sciences, University of Washington, Seattle, WA, USA.8 Department of Radiology, University of Washington, Seattle, WA, USA Department of Neurology, University of Washington, Seattle, WA, USA.

7 Department of Neurology, Swedish Medical Center, Seattle, WA, USA.

6 Department of Psychosocial and Community Health, University of Washington, Seattle, WA, USA.

5 Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.

There are some repair job on it and small shallow chipping. The piece is in over good vintage condition with some imperfection.

The dish was in production from 1960-1969.

Lisa Larson design several wall plaque from the late 50s to late 80s. 4 Department of Radiology and Imaging Sciences and the Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA. The listing is for a beautiful ceramic bird wall plaque / dish designed by Lisa Larson for Gustavsberg.3 Department of Medicine, University of Washington, Seattle, WA, USA.Electronic address: 2 VA Puget Sound Health Care System, Geriatric Research Education and Clinical Center, Seattle, WA, USA Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA. 1 Department of Medicine, University of Washington, Seattle, WA, USA.

Larson late bird